Frederic Jaisser Selected Research

Mineralocorticoid Receptors (Mineralocorticoid Receptor)

10/2022	Roles of Mineralocorticoid Receptors in Cardiovascular and Cardiorenal Diseases.
4/2022	Nonepithelial mineralocorticoid receptor activation as a determinant of kidney disease.
1/2022	Mineralocorticoid Receptor Antagonism Prevents the Synergistic Effect of Metabolic Challenge and Chronic Kidney Disease on Renal Fibrosis and Inflammation in Mice.
1/2022	Mineralocorticoid receptor antagonists in diabetic kidney disease - mechanistic and therapeutic effects.
1/2022	Role of the vascular endothelial sodium channel activation in the genesis of pathologically increased cardiovascular stiffness.
1/2022	Sex-Related Signaling of Aldosterone/Mineralocorticoid Receptor Pathway in Calcific Aortic Stenosis.
1/2021	The Mineralocorticoid Receptor Antagonist Eplerenone Suppresses Interstitial Fibrosis in Subcutaneous Adipose Tissue in Patients With Type 2 Diabetes.
7/2020	Beneficial Effects of Mineralocorticoid Receptor Antagonism on Myocardial Fibrosis in an Experimental Model of the Myxomatous Degeneration of the Mitral Valve.
1/2020	Vascular and inflammatory mineralocorticoid receptors in kidney disease.
1/2020	A New Role for the Aldosterone/Mineralocorticoid Receptor Pathway in the Development of Mitral Valve Prolapse.

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Frederic Jaisser Research Topics

Disease

19	Fibrosis (Cirrhosis) 04/2022 - 05/2002
14	Heart Failure 01/2019 - 05/2002
13	Inflammation (Inflammations) 10/2022 - 12/2008
12	Hypertension (High Blood Pressure) 10/2021 - 10/2007
8	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 11/2005
6	Chronic Renal Insufficiency 04/2022 - 05/2011
6	Obesity 01/2022 - 08/2015
5	Diabetic Nephropathies (Diabetic Nephropathy) 01/2022 - 03/2012
5	Hyperkalemia 11/2021 - 01/2016
4	Kidney Diseases (Kidney Disease) 04/2022 - 05/2011
4	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2017
4	Heart Diseases (Heart Disease) 07/2020 - 06/2005
4	Myocardial Infarction 01/2019 - 02/2012
4	Atrophy 01/2019 - 09/2007
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2018 - 03/2012
3	Insulin Resistance 08/2018 - 03/2012
3	Cardiac Arrhythmias (Arrythmia) 12/2013 - 10/2007
2	Albuminuria 01/2022 - 02/2012
2	Aortic Valve Stenosis (Aortic Stenosis) 01/2022 - 01/2018
2	Metabolic Diseases (Metabolic Disease) 01/2022 - 11/2019
2	Vascular Calcification 01/2021 - 11/2019
2	Wounds and Injuries (Trauma) 01/2020 - 10/2016
2	Vascular Diseases (Vascular Disease) 11/2019 - 10/2018
2	Vascular Remodeling 10/2019 - 02/2011
2	Ischemia 01/2019 - 01/2015
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2019 - 01/2018
2	Cachexia 01/2019 - 04/2014
2	Acute Kidney Injury (Acute Renal Failure) 01/2019 - 01/2016
2	Cardiomyopathies (Cardiomyopathy) 01/2019 - 01/2012
2	Neoplasms (Cancer) 01/2019 - 04/2014
2	Cardiomegaly (Heart Hypertrophy) 10/2017 - 01/2012
2	Uveitis 01/2012 - 08/2011
2	Macular Edema 08/2011 - 09/2010
1	Disease Progression 04/2022
1	Uremia 01/2021
1	Mitral Valve Prolapse 01/2020
1	Vascular System Injuries 11/2019
1	Thrombosis (Thrombus) 11/2019
1	Intracranial Arteriosclerosis (Cerebral Atherosclerosis) 11/2019
1	Pulmonary Hypertension 11/2019
1	Papilledema 10/2019
1	Glomerulonephritis 01/2019
1	Macular Degeneration (Age-Related Maculopathy) 01/2019
1	Choroidal Neovascularization 01/2019
1	Weight Loss (Weight Reduction) 01/2019
1	Vision Disorders (Hemeralopia) 01/2019

Drug/Important Bio-Agent (IBA)

34	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 10/2022 - 05/2002
22	AldosteroneIBA 01/2022 - 06/2005
10	Mineralocorticoid Receptor AntagonistsIBA 01/2022 - 01/2015
9	Spironolactone (Aldactone)FDA LinkGeneric 10/2021 - 05/2011
7	Eplerenone (Inspra)FDA LinkGeneric 10/2021 - 05/2011
6	MineralocorticoidsIBA 11/2017 - 06/2005
5	SaltsIBA 10/2019 - 11/2005
4	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2004
4	CollagenIBA 01/2021 - 12/2008
4	Hormones (Hormone)IBA 10/2018 - 01/2004
4	GlucocorticoidsIBA 07/2015 - 10/2007
3	Messenger RNA (mRNA)IBA 01/2021 - 05/2002
3	Biomarkers (Surrogate Marker)IBA 01/2019 - 05/2014
3	Galectin 3 (LGALS3)IBA 01/2019 - 10/2015
2	Insulin (Novolin)FDA Link 01/2022 - 08/2018
2	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 08/2018
2	SodiumIBA 01/2022 - 10/2019
2	Ion Channels (Ion Channel)IBA 01/2021 - 06/2005
2	Endothelin-1 (Endothelin 1)IBA 11/2019 - 11/2015
2	SirtuinsIBA 10/2019 - 01/2019
2	PotassiumIBA 01/2019 - 01/2016
2	finerenoneIBA 10/2018 - 01/2017
2	LectinsIBA 01/2018 - 10/2015
2	ProteomeIBA 01/2017 - 01/2017
2	Clobetasol (Clobetasol Propionate)FDA LinkGeneric 10/2016 - 07/2015
2	EndotoxinsIBA 01/2012 - 08/2011
1	ElectrolytesIBA 04/2022
1	Therapeutic UsesIBA 01/2022
1	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2022
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2022
1	Angiotensin Receptor AntagonistsIBA 01/2022
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2022
1	SymportersIBA 01/2022
1	Gonadal Steroid Hormones (Sex Hormones)IBA 11/2021
1	KBP-5074IBA 10/2021
1	calcium phosphateIBA 01/2021
1	MineralsIBA 01/2021
1	NorfenfluramineIBA 07/2020
1	Collagen Type I (Type I Collagen)IBA 07/2020
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2020
1	Small Interfering RNA (siRNA)IBA 01/2020
1	Nitric Oxide Synthase (NO Synthase)IBA 01/2020
1	Oxidants (Oxidizing Agents)IBA 01/2020
1	Pioglitazone (Actos)FDA Link 11/2019
1	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 11/2019
1	Sirtuin 1IBA 10/2019
1	RNA (Ribonucleic Acid)IBA 10/2019
1	nasIBA 10/2019
1	AMP-Activated Protein KinasesIBA 10/2019
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019
1	Calcineurin InhibitorsIBA 01/2019
1	Lipocalin-2IBA 01/2019

Therapy/Procedure

4	Therapeutics 01/2022 - 01/2018
1	Injections 01/2019